Csf partner

Die drei Partner der Kanzlei C+S: Kristoffer Soll, Michael Carstensen und Elena Steinhäuser Die Kanzlei Die C+S Partnerschaft (bis 2014: CSF Partnerschaft) wurde im Jahre 1972 gegründet und hat sich schon früh als eine der größten Wirtschaftsprüfungs- und Steuerberatungsgesellschaften im Süden Hamburgs etabliert. Info4cAG and CSF Solutions GmbH arrange collaboration for using PEP DeskTM for business partner screening within Zerberus®-Solutions Additional PEP-Content by info4c for your business partner screening: info4c is the global provider for high-quality and individualized Compliance-Information. Jane Stallman, Senior Partner. ... Since joining CSF in 2014, Robert has consulted to important CSF clients such as Alameda County General Services, California State Parks Foundation, Sandia National Laboratories, Lake County Tribal Health Consortium, Point Blue Conservation Science and Santa Clara Valley Water District. ... CSF Inox S.p.A., established in 1970 in Montecchio Emilia, a small town in northern Italy, is today a leading company in both Italy and Europe in the production of pumps primarily designed for the food & beverage, dairy, chemical and pharmaceutical industries. Owner/Partner CSF Attorneys. Oct 1999 – Present 21 years. Education. University of Cape Town. University of Cape Town BA and Bachelor of Laws (LLB) 1985 – 1990. Rondebosch Boys High School matric. 1980 – 1984. Languages. Afrikaans. View Timothy’s full profile. See who you know in common; Children’s Scholarship Fund (CSF) is pleased to announce the publication of Opportunity and Hope: Transforming Children’s Lives through Scholarships by Naomi Schaefer Riley, author, former Wall Street Journal editor, and columnist for the New York Post.. In this new book, Ms. Riley profiles ten young men and women from across America whose lives were improved when they were awarded ... CSF partner programs award and administer scholarships to local families using the CSF model. While CSF often provides management and financial support, local organizations are experts in their respective communities and regions. Each organization also conducts its own local fundraising campaigns to help bridge the gap between those in need and ...

Chance me for UCs!!

2020.09.08 05:50 Acrobatic_Practice36 Chance me for UCs!!

Demographics: NorCal, competitive rich white school, no hooks
Intended Major(s): computer science, applied math
ACT/SAT/SAT II: nope, covid
UW/W GPA and Rank: UC: 3.95 UW / 4.41 capped W / 4.87 uncapped W
Rank: 5/550
Coursework: Maximum rigor possible
11: AP Chem(4), AP Euro(5), AP Spanish(3)
12: APUSH, AP Lit, AP Calc AB/BC, AP Physics C, AP Gov, AP Stats
CC courses: CS, Physics, Communication, Art History
Awards: Placed 3rd in Science Olympiad Codebusters Regionals(competed against nationally recognized schools), Placed 5th in FBLA Math regionals(state qualified), NHS(selective criteria), CSF, AP scholar(not sure which one)
Extracurriculars: Science Olympiad(potential vice president this year if not canceled), Key Club Treasurer-55 hours, Founder of web App to help Math students-30k uses worldwide, Personal Coding projects(many are math related) with github portfolio, Moocs-certified cs50 and working on machine learning, VP of coding club
Essays: Assuming 7/10(trying to convey a theme throughout my application as well as qualities UCs look for)
Schools: UC Berkeley L&S(applied math, will do CS double major once there but I heard even though they don’t consider major, they reject more CS), UCLA Engineeing(Computer science and engineering), other UCs for safeties(CS mostly)
Also Stanford and Caltech high reaches(computational math)
———————
Ya so basically I’ll elaborate on a few things. So my coding hobby-basically I found interest in coding when I self taught myself and I made a variety of calculators’ source code in my free time. I coded a portfolio of my best works and will link on application
Then on my web app, basically I developed a web app to help my friend solve quadratics at first but then I started to expand it to have more features and it’s up to like 30k uses worldwide cause I promote it on social media. Also will link on application
Then for the moocs I just completed and got a certificate in cs50 by Harvard and I’m currently working on machine learning by Stanford.
For key club, we help teachers and staff every week and also host community events. I’m in charge of like the budget and everything to do with money.
Science Olympiad is basically we do research on specific events and study them with teammates for like half the year then we have 1 regional competition at the end and if the whole team does good we go to states(but the whole team sucks, only me and my partner won an award)
Also me and my friend are starting a coding club, not sure how big it will get but I’m VP
Also I’m trying to convey a theme throughout my application in essays which is like “using my knowledge in stem to help serve the academic community” which like encompasses all my ECs and hobbies and passions
If you need any additional info just let me know
submitted by Acrobatic_Practice36 to ReverseChanceMe [link] [comments]


2020.08.17 02:34 PotentialStrike2 Requesting C-section under general anesthesia

Hi everyone! Hoping to get some much needed insight...
I am a 29 year old female in Toronto, Canada with the condition Idiopathic Intracranial Hypertension (IIH). I suffer from debilitating headaches and I've got papillidema from the increased pressure. I've had multiple lumbar punctures in the past- all leading to CSF leaks, low pressure headaches and blood patches. Needless to say I am very apprehensive to have anything go near my spinal cord due to the physical and emotional trauma caused.
I have been avoiding the idea of pregnancy for a long time as I know that it could potentially increase my symptoms and lead to further damage to my optic nerves and thus vision loss. Most of my symptoms are currently made worse by hormonal changes around my period so I'm worried about how pregnancy hormones will affect my pregnancy.
With all this said, I am getting to the point where I desperately want to have a child with my partner and it is a life change that is very imminent. My concerns now mainly lie with the actual delivery process.
My main question is: given my health condition, am I allowed to request a cesarean section under general anesthesia? I absolutely do not feel comfortable with an epidural or spinal block and absolutely do not feel comfortable with a vaginal delivery as CSF pressure raises with pushing.
I am terrified and apprehensive to get pregnant unless I know that my preferred method of delivery/anesthesia will be honored. I don't want to put myself more at risk.
I hope I can get some insightful answers! Thank you in advance :)
submitted by PotentialStrike2 to AskDocs [link] [comments]


2020.07.25 06:29 ntidwell98 Thorough DD $IBIO

Who is IBIO?


IBIO CDMO


CDMO SERVICES


FastPharming Technology





FastGlycaneering (Glycan-Engineering)


Why FastGlycaneering?




PIPELINE





Advantages of IBIO-400







Partners


Team


FINANCIALS


CONCERNS:
· A few very important quotes from the 10-Q filed 05/15/2020
· “To become and remain profitable, the Company must succeed in commercializing its technologies, alone or with its licensees, the service offerings provided by its CDMO facility, and in developing and eventually commercializing products that generate significant revenue. In addition, profitability will depend on continuing to attract and retain customers for the development, manufacturing and technology transfer services offered by the Company.”
· “Based on the total cash on hand of approximately $10.0 million as of March 31, 2020, combined with subsequent purchases of the Company’s common stock by Lincoln Park through the date of the filing of this report totaling approximately $10 million, we believe the Company has adequate cash on hand to support the Company’s activities for at least one year from this report date.”



CONCLUSION
I am bullish medium/long term on IBIO if they can mange to effectively license their technology platforms as well as continue to further research and develop their vaccination candidates. IF either IBIO 200 and/or 201 show positive results soon in combating COVID, this is could lead to government funding (possible OWS) as the ability to mass produce 500 million vaccines annually on their own is huge. They have burned through a good bit of cash and are reliant on some key factors, but overall with the direction the world is going and the increased popularity/demand for vaccines, I am positive on the future outlook of IBIO for now.
I own a position of 1050 shares @ 4.49 and plan to hold for 1+ year.
Hope everyone enjoys and as always I invite comments, concerns, and additional information I missed. Best of luck to everyone with their trades and have a great weekend!


EDIT 1: July 29, 2020: IBIO filed an 8-K. Within the 8-K, it states "The Company plans to participate in media interviews and make a series of investor presentations over the next several weeks, during which it intends to discuss the preliminary preclinical data set forth in Exhibit 99.1, which is incorporated herein by reference." (Page 3, Item 8.01). In my opinion, you wouldn't participate in media interviews and prepare for investor presentations if you had negative preliminary data or doubts. I remain upbeat about the next few months.

EDIT 2: Ibio activated SAM funding on 07/31/2020

EDIT 3: Going back over my DD I realize I have left out 3 very important relationships iBio has formed this year.
  1. iBio Selected by IBM Watson Health for the use of IBM Clinical Development Solution at No Cost to help Support clinical COVID-19 Vaccine Candidates
    1. IBM Watson Health has selected iBio to receive 18 months of use of the IBM Clinical Development (ICD) solution, free-of-charge.
  2. iBio Expands COVID-19 Vaccine Collaboration to Include the Infectious Disease Research Institute (Seattle).
    1. Signed two Master Services Agreements (the MSAs”) and a Memorandum of Understanding (the “MoU”) with the Infectious Disease Research Institute (“IDRI”) in support of iBio’s SARS-CoV-2 Virus-Like Particle (“VLP”) vaccine development.
    2. IDRI will support pre-clinical development and provide clinical trial oversight, while iBio will provide process development and manufacturing services to IDRI, as needed.
    3. Additionally, the MoU calls for iBio and IDRI to establish a separate, additional agreement within the next 60 days if the Company opts to include one of IDRI’s novel adjuvants in the COVID-19 vaccine development program (“IBIO-200”).
    4. The MSAs and the MoU integrate IDRI into iBio’s collaboration with the Texas A&M University System to create a strong partnership that brings deep experience and advanced technologies and capabilities to the task of moving IBIO-200 into the clinic.
  3. Joined the National Institute for Innovation in Manufacturing Biopharmaceuticals (“NIIMBL”), one of 14 institutes in the Manufacturing USA Network.
    1. NIIMBL is a public-private partnership that aims to accelerate biopharmaceutical manufacturing innovations and establish an international, leading workforce to fundamentally strengthen the U.S. biopharmaceutical industry.
    2. NIIMBL has an extensive network of more than 140 academic and industry partners within the U.S., including biopharmaceutical companies, academic institutions, research laboratories and non-profit organizations.

EDIT 4:
Alright, so this is ALL THEORY again but I can't help but post to get everyones opinion.
I was going back and watching Trump's Press Conference from July 28th where he talks about "producing 100 million vaccines as soon as a vaccine is approved and then 500 million doses shortly after."
So, the 500 million dose approximation Trump stated caught my attention because that is the same approximation iBio has claimed previously and was reiterated by Tom Isett in his The Hill interview.
What REALLY caught my attention was at 0:21 to 0:45. Trump begins to ramble on about "logistically using the military", a group of people who's "whole life is based around logistics", and them being able to do it very very quickly. Well at the end Trump says "a very very talented General is in charge."
First, the Department of Defense built the 130,000 sq ft CDO that iBio acquired in Bryan, Texas. So they know it exist.
Second, guess who are on the Board of Directors at iBio, Inc.?
General (Ret.) James T. Hill was the Commander of the 4-Star United States Southern Command, reporting directly to the President and Secretary of Defense at the time of his retirement from active duty. As such he led all U.S. military forces and operations in Central America, South America and the Caribbean, worked directly with U.S. Ambassadors, foreign heads of state, key Washington decision-makers, foreign senior military and civilian leaders, developing and executing United States policy. His responsibilities included management, development and execution of plans and policy within the organization including programming, communications, manpower, operations, logistics and intelligence. General Hill's experience implementing plans and policies within diverse geographic regions and his insights regarding the conduct of business affairs in Central and South America is a key resource for us.

Philip K. Russell, M.D. served in the U.S. Army Medical Corps from 1959 to 1990, pursuing a career in infectious disease and tropical medicine research. Following his military service, Dr. Russell joined the faculty of Johns Hopkins University's School of Hygiene and Public Health and worked closely with the World Health Organization as special advisor to the Children's Vaccine Initiative. He was founding board member of the International AIDS Vaccine Initiative and was an advisor to the Bill & Melinda Gates Foundation. He has served on numerous advisory boards of national and international agencies, including the Centers for Disease Control ("CDC"), the National Institutes of Health ("NIH") and the Institute of Medicine. Dr. Russell is a past Chairman of the Albert B. Sabin Vaccine Institute. Dr. Russell's extensive experience and expertise in the field of infectious diseases and his association with leading governmental and not-for-profit entities engaged in pioneering work throughout the world provides us with invaluable insights into priorities for these entities and business development opportunities for us.

EDIT 5:
Here are a few things I’ve been looking into lately in regard to iBio:
First off, The US Government has made investments in programmes such as DARPA’s Blue Angel and other accelerated, large-scale manufacturing efforts for medical countermeasures within the Department of Defense and Department of Health and Human Services to develop capabilities to rapidly respond to any emerging disease or pandemic threat.
[DARPA Effort Speeds Biothreat Response](https://archive.defense.gov/News/NewsArticle.aspx?ID=61520)
This is an article from DoD website from 2010.
This lead me to begin researching G-Con:
Since 2009, G-CON has lead the cleanroom industry, fulfilling pharmaceutical and biopharmaceutical needs and embracing new trends. G-CON designs, builds and installs prefabricated cleanroom PODs for a variety of dimensions and purposes, from laboratory environments to personalized medicines and even production process platforms.
Well I was watching a YouTube video about The GreenVax Project and the construction of the facility in Bryan/College Station that iBio eventually acquires in 2016.
https://youtu.be/T0nukOKUiCo
The same exact clean room solutions that G-Con designs is what Giroir is talking about in the video about being able to move the rooms around due to the air bearings.
EDIT 6:
USDA Confirmation of iBio planting seeds for Human Consumption.
EDIT 5: July 31st, 2020
The U.S. Department of Health and Human Services (HHS) and Department of Defense (DoD) today announced agreements with Sanofi and GlaxoSmithKline (GSK) to support advanced development including clinical trials and large-scale manufacturing of 100 million doses of a COVID-19 investigational adjuvanted vaccine.... The U.S. government also has the ability to acquire up to 500 million additional doses. Is this could be what Trump was referring to?
It very well could be! I’ve stated that this is theory and nothing is for certain.
However, it has been said by many doctors/scientists that it will take many manufactures and vaccines to produce what’s being demanded. Even Trump stated that at his North Carolina COVID press release.
Things that stood out to me HHS, DoD article.
I could still very well be wrong. This is a personal opinion based on my own research and conclusions.

EDIT 7: August 6th, 2020
Trump signs executive order requiring government to buy ‘essential’ drugs from U.S. companies
EDIT 8: August 7th, 2020
SEC FORM SC 13D/A Eastern Capital Ltd. [Amend] General statement of acquisition of beneficial ownership.

submitted by ntidwell98 to EducatedInvesting [link] [comments]


2020.07.25 06:19 ntidwell98 Thorough DD $IBIO

Who is IBIO?



IBIO CDMO


CDMO SERVICES


FastPharming Technology






FastGlycaneering (Glycan-Engineering)


Why FastGlycaneering?




PIPELINE






Advantages of IBIO-400







Partners


Team


FINANCIALS


CONCERNS:
· A few very important quotes from the 10-Q filed 05/15/2020
· “To become and remain profitable, the Company must succeed in commercializing its technologies, alone or with its licensees, the service offerings provided by its CDMO facility, and in developing and eventually commercializing products that generate significant revenue. In addition, profitability will depend on continuing to attract and retain customers for the development, manufacturing and technology transfer services offered by the Company.”
· “Based on the total cash on hand of approximately $10.0 million as of March 31, 2020, combined with subsequent purchases of the Company’s common stock by Lincoln Park through the date of the filing of this report totaling approximately $10 million, we believe the Company has adequate cash on hand to support the Company’s activities for at least one year from this report date.”

CONCLUSION
I am bullish medium/long term on IBIO if they can mange to effectively license their technology platforms as well as continue to further research and develop their vaccination candidates. IF either IBIO 200 and/or 201 show positive results soon in combating SARS-CoV-2, this is could lead to government funding (possible OWS) as the ability to mass produce 500 million vaccines annually on their own is huge. They have burned through a good bit of cash and are reliant on some key factors, but overall with the direction the world is going and the increased popularity/demand for vaccines, I am positive on the future outlook of IBIO for now.

I own a position of 200 shares @ 5.29 and plan to hold until a SP of $15-20

Hope everyone enjoys and as always I invite comments, concerns, and additional information I missed. Best of luck to everyone with their trades and have a great weekend!
submitted by ntidwell98 to pennystocks [link] [comments]


2020.07.24 03:45 NinjaNerdFinder [Hiring] Director of Governance, Risk and Compliance (GRC) - Remote location

We are [Hiring] a Director of Governance, Risk and Compliance (GRC) - Remote location
Location: Remote – US
Salary: $90k-$125k (based on experience)
Reports to: COO
Primary Function: Under the direction of the COO, the Director of Governance, Risk and Compliance (GRC) will be responsible for developing, implementing, operating and monitoring the Company’s Information Security Risk & Privacy Program in accordance with all applicable Federal and state laws, rules and regulatory requirements. The Director GRC will function as an independent and objective body that reviews and evaluates compliance issues and concerns within the organization and produces corrective action plans as necessary.
This position will work to maintain, and continue to enhance, Company culture of compliance and behaviors with close collaboration with internal and external business partners.
Job Scope and Major Responsibilities:
Qualifications:
submitted by NinjaNerdFinder to forhire [link] [comments]


2020.06.18 04:13 boccherini-trader Could Alector (ALEC) Get Us Over the Mountain of Past R&D Failures? [PART 2]

Summary: Denali Therapeutics (NASDAQ: DNLI) and Alector (NASDAQ: ALEC) are two high-profile companies taking a new angle on neurodegenerative diseases like Parkinson’s and Alzheimer’s Disease (PD & AD), notoriously tough nuts to crack. We are cautiously excited about a handful of innovative companies including the two highlighted here (we also previously wrote about Passage Bio (NASDAQ: PASG), a gene therapy CNS player we took a position in).
ALEC leverages association studies to identify genetic targets and biomarkers for immuno-neurology therapies. DNLI also takes a genetically-driven approach to target selection, and possesses a proprietary blood-brain barrier (BBB) transport platform. A look at their pipelines reveals some overlapping targets (progranulin in FTD, TREM2 in AD), reflecting the similar philosophical starting point for these companies. This article will focus on the case for and against ALEC.
Alector Key Takeaways
The Case for ALEC:
The Case Against ALEC:
Disclosure:
We do not own shares of Alector or Denali Therapeutics. This article expresses our own opinions, not Alector’s, Denali’s, or any other party’s opinion. We are not receiving compensation for this report. We do not have a business relationship with the companies mentioned in this report.
submitted by boccherini-trader to wallstreetbets [link] [comments]


2020.06.18 04:12 boccherini-trader Could Alector (ALEC) Get Us Over the Mountain of Past R&D Failures? [PART 2]

Summary: Denali Therapeutics (NASDAQ: DNLI) and Alector (NASDAQ: ALEC) are two high-profile companies taking a new angle on neurodegenerative diseases like Parkinson’s and Alzheimer’s Disease (PD & AD), notoriously tough nuts to crack. We are cautiously excited about a handful of innovative companies including the two highlighted here (we also previously wrote about Passage Bio (NASDAQ: PASG), a gene therapy CNS player we took a position in).
ALEC leverages association studies to identify genetic targets and biomarkers for immuno-neurology therapies. DNLI also takes a genetically-driven approach to target selection, and possesses a proprietary blood-brain barrier (BBB) transport platform. A look at their pipelines reveals some overlapping targets (progranulin in FTD, TREM2 in AD), reflecting the similar philosophical starting point for these companies. This article will focus on the case for and against ALEC.
Alector Key Takeaways
The Case for ALEC:
The Case Against ALEC:
Disclosure:
We do not own shares of Alector or Denali Therapeutics. This article expresses our own opinions, not Alector’s, Denali’s, or any other party’s opinion. We are not receiving compensation for this report. We do not have a business relationship with the companies mentioned in this report.
submitted by boccherini-trader to stocks [link] [comments]


2020.06.18 04:11 boccherini-trader Could Alector (ALEC) Get Us Over the Mountain of Past R&D Failures? [PART 2]

Summary: Denali Therapeutics (NASDAQ: DNLI) and Alector (NASDAQ: ALEC) are two high-profile companies taking a new angle on neurodegenerative diseases like Parkinson’s and Alzheimer’s Disease (PD & AD), notoriously tough nuts to crack. We are cautiously excited about a handful of innovative companies including the two highlighted here (we also previously wrote about Passage Bio (NASDAQ: PASG), a gene therapy CNS player we took a position in).
ALEC leverages association studies to identify genetic targets and biomarkers for immuno-neurology therapies. DNLI also takes a genetically-driven approach to target selection, and possesses a proprietary blood-brain barrier (BBB) transport platform. A look at their pipelines reveals some overlapping targets (progranulin in FTD, TREM2 in AD), reflecting the similar philosophical starting point for these companies. This article will focus on the case for and against ALEC.
Alector Key Takeaways
The Case for ALEC:
The Case Against ALEC:
Disclosure:
We do not own shares of Alector or Denali Therapeutics. This article expresses our own opinions, not Alector’s, Denali’s, or any other party’s opinion. We are not receiving compensation for this report. We do not have a business relationship with the companies mentioned in this report.
submitted by boccherini-trader to StockMarket [link] [comments]


2020.06.18 04:10 boccherini-trader Could Alector (ALEC) Get Us Over the Mountain of Past R&D Failures? [PART 2]

Summary: Denali Therapeutics (NASDAQ: DNLI) and Alector (NASDAQ: ALEC) are two high-profile companies taking a new angle on neurodegenerative diseases like Parkinson’s and Alzheimer’s Disease (PD & AD), notoriously tough nuts to crack. We are cautiously excited about a handful of innovative companies including the two highlighted here (we also previously wrote about Passage Bio (NASDAQ: PASG), a gene therapy CNS player we took a position in).
ALEC leverages association studies to identify genetic targets and biomarkers for immuno-neurology therapies. DNLI also takes a genetically-driven approach to target selection, and possesses a proprietary blood-brain barrier (BBB) transport platform. A look at their pipelines reveals some overlapping targets (progranulin in FTD, TREM2 in AD), reflecting the similar philosophical starting point for these companies. This article will focus on the case for and against ALEC.
Alector Key Takeaways
The Case for ALEC:
The Case Against ALEC:
Disclosure:
We do not own shares of Alector or Denali Therapeutics. This article expresses our own opinions, not Alector’s, Denali’s, or any other party’s opinion. We are not receiving compensation for this report. We do not have a business relationship with the companies mentioned in this report.
submitted by boccherini-trader to pennystocks [link] [comments]


2020.06.18 04:08 boccherini-trader Could Alector (ALEC) Get Us Over the Mountain of Past R&D Failures? [PART 2]

Summary: Denali Therapeutics (NASDAQ: DNLI) and Alector (NASDAQ: ALEC) are two high-profile companies taking a new angle on neurodegenerative diseases like Parkinson’s and Alzheimer’s Disease (PD & AD), notoriously tough nuts to crack. We are cautiously excited about a handful of innovative companies including the two highlighted here (we also previously wrote about Passage Bio (NASDAQ: PASG), a gene therapy CNS player we took a position in).
ALEC leverages association studies to identify genetic targets and biomarkers for immuno-neurology therapies. DNLI also takes a genetically-driven approach to target selection, and possesses a proprietary blood-brain barrier (BBB) transport platform. A look at their pipelines reveals some overlapping targets (progranulin in FTD, TREM2 in AD), reflecting the similar philosophical starting point for these companies. This article will focus on the case for and against ALEC.
Alector Key Takeaways
The Case for ALEC:
The Case Against ALEC:
Disclosure:
We do not own shares of Alector or Denali Therapeutics. This article expresses our own opinions, not Alector’s, Denali’s, or any other party’s opinion. We are not receiving compensation for this report. We do not have a business relationship with the companies mentioned in this report.
submitted by boccherini-trader to investing [link] [comments]


2020.05.22 12:17 annispy [STORE] Karambit SAPPHIRE 0.0129, Pandora's Box FT, Butterfly Fade, Karambit Lore MW, Karambit CH FN #149, Glock Fade 92% 0.018, Butterfly Slaughter MW, Bayo Tiger 0.007, Specialist Fade FT, Specialist Foundation FT

Looking to trade or sell some of my items
B/O are mentioned in TB Arcanas.
Prices negotiable on all, just add me or send an offer (No stupid lowballs please)
Karambit Sapphire FN 0.0129 really clean corner
B/O: 225 Arcs Screenshot ^^^
Pandora's Box FT 0.376
B/O: 62 Arcs ^^^
Butterfly Fade 84% FN 0.026
B/O: 39 Arcs Screenshot ^^^
Karambit Lore MW 0.142
B/O: 35 Arcs ^^^
Karambit CH FN 0.049 #149 very underrated pattern
B/O: 28 Arcs Screenshot ^^^
Glock Fade 92% FN 0.018
B/O: 29 Arcs Screenshot ^^^
Butterfly Slaughter MW 0.120
B/O: 24 Arcs ^^^
Bayonet Tiger Tooth FN 0.007
B/O: 15 Arcs ^^^
Specialist Fade FT 0.368
B/O: 19 Arcs ^^^
Specialist Foundation FT 0.357
B/O: 11 Arcs ^^^
Profile Add me
Also will gladly take Hooks @ 29 TB
Accepting skin offers with overpay as well
submitted by annispy to GlobalOffensiveTrade [link] [comments]


2020.05.15 17:19 JustSomeStonksBoi SELLAS GOT 2 CANCER VACCINES INCOMING

Trend reversal and several upcoming catalysts : SLS
Market cap now <$20M – should be $150M - $250M right now
SELLAS Life Sciences Group, Inc. (SLS) is a late-stage clinical biopharmaceutical company focused on the development of novel cancer immunotherapies for a broad range of cancer indications with TWO Phase 3 ready cancer vaccines : GPS and NPS. Both have proven to be safe and well-tolerated and achieved very impressive results so far. Impressive list of partners funding the ongoing trials.
GPS :
• In February 2020, SELLAS announced positive follow-up data from its Phase 1/2 study of GPS in CR2 AML patients. The final data show a median overall survival (OS) of 21.0 months, at a median follow-up of 30.8 months, in patients receiving GPS compared to 5.4 months in patients treated with best standard care (p-value < 0.02). GPS therapy continued to be well-tolerated throughout the study.
• In February 2020, SELLAS announced the enrollment of the first patient in an investigator-sponsored clinical trial of GPS in combination with Bristol-Myers Squibb’s anti-PD-1 therapy, nivolumab (Opdivo®), in patients with MPM.
• In January 2020, SELLAS announced that it commenced patient screening for its pivotal Phase 3 REGAL study of GPS in patients with AML in CR2.
NPS :
• In March 2020, SELLAS announced preliminary antigen-specific immune response data from a Phase 2 randomized investigator-sponsored trial of NPS in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF) in women with ductal carcinoma in situ (DCIS) of the breast who are HLA-A2+ or A3+ positive, express HER2 at IHC 1+, 2+, or 3+ levels, and are pre- or post-menopausal. Preliminary data show an 11-fold increase in a CD8 cytotoxic T-lymphocytes immune response in patients who received a single dose of NPS compared to baseline. The final data is being further analyzed by the National Institute of Health, MD Anderson Cancer Center and the study principal investigator, Dr. Elizabeth Mittendorf, MD, PhD of the Dana-FarbeBrigham and Women’s Cancer Center, and will be presented at an upcoming medical conference.
• In March 2020, SELLAS announced that final results from the efficacy and safety data analysis of the Phase 2b independent investigator-sponsored clinical trial of the combination of trastuzumab (Herceptin®) +/- NPS targeting HER2 low-expressing breast cancer patient cohorts, including patients with triple negative breast cancer (TNBC), were recently published in the peer reviewed journal, Clinical Cancer Research. With regard to the TNBC patient cohort, the data analysis shows:
- Disease-free survival (DFS) landmark rate at 24 months for patients treated with NPS plus trastuzumab (n=53) was 92.6% compared to 70.2% for those treated with trastuzumab alone (n=44), a clinically and statistically significant improvement.
- There was a statistically significant reduction of 71.9% (p=0.01) in the frequency of clinically detected recurrences in patients treated with the combination (NPS plus trastuzumab) versus trastuzumab alone.
- The combination was generally well-tolerated and there were no clinicopathologic differences between the study groups.
• In February 2020, SELLAS announced that it had finalized the design and plan for a Phase 3 registration-enabling study of NPS in combination with trastuzumab for the treatment of patients with TNBC in the adjuvant setting after standard treatment, following feedback from a Type C review with the FDA. SELLAS is actively pursuing out-licensing opportunities to fund and conduct the future clinical development of NPS.
TLDR; Sellas got 2 very promising cancer vaccines -> will get FDA approved -> MOON.
Market Cap is 20 Million, shares around $3
Market Cap should be around 150 - 200 Million, SHARES ARE GONNA MOON TO MINIMUM $20
Patience will be rewarded
Sources :
Recent shareholders letter: https://s22.q4cdn.com/485546146/files/doc_downloads/Shareholder_LetteSLS-Shareholder-Update.pdf
First Q Financial results and Bussiness Update :
https://finance.yahoo.com/news/sellas-life-sciences-reports-first-203303422.html
Partners : https://www.sellaslifesciences.com/partnerships/default.aspx
submitted by JustSomeStonksBoi to options [link] [comments]


2020.05.15 15:28 JustSomeStonksBoi SELLAS GOT 2 CANCER VACCINES INCOMING

Trend reversal and several upcoming catalysts : SLS

Market cap now <$20M – should be $150M - $250M right now
SELLAS Life Sciences Group, Inc. (SLS) is a late-stage clinical biopharmaceutical company focused on the development of novel cancer immunotherapies for a broad range of cancer indications with TWO Phase 3 ready cancer vaccines : GPS and NPS. Both have proven to be safe and well-tolerated and achieved very impressive results so far. Impressive list of partners funding the ongoing trials.

GPS :

• In February 2020, SELLAS announced positive follow-up data from its Phase 1/2 study of GPS in CR2 AML patients. The final data show a median overall survival (OS) of 21.0 months, at a median follow-up of 30.8 months, in patients receiving GPS compared to 5.4 months in patients treated with best standard care (p-value < 0.02). GPS therapy continued to be well-tolerated throughout the study.
• In February 2020, SELLAS announced the enrollment of the first patient in an investigator-sponsored clinical trial of GPS in combination with Bristol-Myers Squibb’s anti-PD-1 therapy, nivolumab (Opdivo®), in patients with MPM.
• In January 2020, SELLAS announced that it commenced patient screening for its pivotal Phase 3 REGAL study of GPS in patients with AML in CR2.

NPS :
• In March 2020, SELLAS announced preliminary antigen-specific immune response data from a Phase 2 randomized investigator-sponsored trial of NPS in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF) in women with ductal carcinoma in situ (DCIS) of the breast who are HLA-A2+ or A3+ positive, express HER2 at IHC 1+, 2+, or 3+ levels, and are pre- or post-menopausal. Preliminary data show an 11-fold increase in a CD8 cytotoxic T-lymphocytes immune response in patients who received a single dose of NPS compared to baseline. The final data is being further analyzed by the National Institute of Health, MD Anderson Cancer Center and the study principal investigator, Dr. Elizabeth Mittendorf, MD, PhD of the Dana-FarbeBrigham and Women’s Cancer Center, and will be presented at an upcoming medical conference.
• In March 2020, SELLAS announced that final results from the efficacy and safety data analysis of the Phase 2b independent investigator-sponsored clinical trial of the combination of trastuzumab (Herceptin®) +/- NPS targeting HER2 low-expressing breast cancer patient cohorts, including patients with triple negative breast cancer (TNBC), were recently published in the peer reviewed journal, Clinical Cancer Research. With regard to the TNBC patient cohort, the data analysis shows:
- Disease-free survival (DFS) landmark rate at 24 months for patients treated with NPS plus trastuzumab (n=53) was 92.6% compared to 70.2% for those treated with trastuzumab alone (n=44), a clinically and statistically significant improvement.
- There was a statistically significant reduction of 71.9% (p=0.01) in the frequency of clinically detected recurrences in patients treated with the combination (NPS plus trastuzumab) versus trastuzumab alone.
- The combination was generally well-tolerated and there were no clinicopathologic differences between the study groups.
• In February 2020, SELLAS announced that it had finalized the design and plan for a Phase 3 registration-enabling study of NPS in combination with trastuzumab for the treatment of patients with TNBC in the adjuvant setting after standard treatment, following feedback from a Type C review with the FDA. SELLAS is actively pursuing out-licensing opportunities to fund and conduct the future clinical development of NPS.

TLDR; Sellas got 2 very promising cancer vaccines -> will get FDA approved -> MOON.
Market Cap is 20 Million, shares around $3
Market Cap should be around 150 - 200 Million, SHARES ARE GONNA MOON TO MINIMUM $20
Patience will be rewarded
Sources :
Recent shareholders letter: https://s22.q4cdn.com/485546146/files/doc_downloads/Shareholder_LetteSLS-Shareholder-Update.pdf
First Q Financial results and Bussiness Update :
https://finance.yahoo.com/news/sellas-life-sciences-reports-first-203303422.html
Partners : https://www.sellaslifesciences.com/partnerships/default.aspx
submitted by JustSomeStonksBoi to pennystocks [link] [comments]


2020.05.07 19:35 kjonesatjaagnet GSK taps experimental arthritis antibody to calm the cytokine storm hitting COVID-19 patients

GlaxoSmithKline is hard at work with partner Sanofi in getting a vaccine tested for COVID-19, but this morning it said it was now also entering the race to treat patients already hit with the disease.
Specifically, the U.K.-based Big Pharma says it has “identified” a monoclonal antibody from its pipeline, anti-GM-CSF (granulocyte macrophage colony-stimulating factor) otilimab, as a “potential treatment for patients who have been hospitalised with severe pulmonary complications related to COVID-19.”
It plans to start midstage testing in the coming weeks in around 800 patients in a randomized, placebo-controlled trial.
The drug is already in trials for arthritis, but like other meds, including some repurposed efforts, GSK hopes its therapy can help those with COVID-19 who are hit with a secondary complication known as a cytokine storm.
This can be fatal and comes as a result of an overreaction of the body’s immune system; it’s also seen in other infections such as influenza.
With SARS-CoV-2, the virus causing the pandemic, immune cells are sent out to the lungs when the virus strikes, which causes inflammation in that area. But sometimes this can go into overdrive and causes hyperinflammation leading to injury or even death in some, and it can also hit younger patients.
In a statement to FierceBiotech, GSK said: “We believe that otilimab may be able to help to block the effects of one of the types of cytokine (known as GM-CSF). We plan to start a phase 2 clinical trial by the end of May.”
As with all experimental drugs, which aren’t of course manufactured to fulfil commercial demand, supply can be an issue, and it’s something we’ve already seen with Gilead’s limited numbers for its recently approved repurposed Ebola drug remdesivir in COVID-19.
GSK tells FierceBiotech that otilimab’s supply is “currently being used for the COVID-19 and RA clinical studies” but that, should the results in COVID-19 go its way, GSK “will explore all options to maximize the supply of otilimab.”
A spokesperson added: “We will work with regulators and manufacturing partners to determine how to provide access of otilimab to patients with COVID-19 who urgently need treatments.”
The pharma wouldn’t answer questions on price and how, if approved, it would be distributed, but said: “We recognize the unprecedented patient need for therapies to treat COVID-19. Our priority is to help find solutions during this global health emergency. If the study with otilimab is positive, we will work with regulators to make the medicine available to patients as quickly as possible.”
The drug entered a phase 3 trial in rheumatoid arthritis last year and was originally developed by MorphoSys. GM-CSF acts on cells, including macrophages (an immune cell type that plays a key role in the inflammatory process), leading to inflammation, joint damage and pain.
Otilimab works by neutralizing the biological function of GM-CSF by blocking the interaction of GM-CSF with its cell surface receptor.
GSK explained that GM-CSF (granulocyte-macrophage colony-stimulating factor) is a cytokine found in high levels in patients with COVID-19. As otilimab works by blocking the effects of GM-CSF, which it says is found in high levels in COVID-19 patients, GSK explained that it will test "whether a single dose of otilimab could dampen the inflammation in patients with COVID-19 pneumonia.”
Originlly published byBen Adams May 7, 2020 FierceBiotech
submitted by kjonesatjaagnet to JAAGNet [link] [comments]


2020.04.15 14:07 chrisphillers Filtering a JSON object

I need to search (well, filter) through the below JSON object - to achieve this suspect I need to convert this into an array - can anyone give any pointers? Object.entries I think will give me no joy.
Thanks v v much.

{ "steve": { "id": "steve", "markdown": "STEVE", "source": "STEVE" }, "46-xy-gonadal-dysgenesis": { "id": "46-xy-gonadal-dysgenesis", "markdown": "![](Wikiproject%20medicine%20logo.png)\n\n46 XY gonadal dysgenesis\n========================\n\n \n\n* * *\n\n* XY gonadal dysgenesis (or Swyer Syndrome) is a type of hypogonadism in a person whose karyotype is 46,XY.\n\n* The person is externally female with streak gonads, and if left untreated, will not experience puberty.\n\n* Such gonads are typically surgically removed (as they have a significant risk of developing tumors) and a typical medical treatment would include hormone replacement therapy.\n\n* The first known step of sexual differentiation of a normal XY fetus is the development of testes.\n\n* The early stages of testicular formation in the second month of gestation requires the action of several genes, of which one of the earliest and most important is SRY, the sex-determining region of the Y chromosome. Mutations of SRY account for many cases of Swyer syndrome.When such a gene is defective, the indifferent gonads fail to differentiate into testes in an XY (genetically male) fetus.\n\n* Without testes, no testosterone or antimllerian hormone (AMH) is produced.\n\n* Without testosterone, the wolffian ducts fail to develop, so no internal male organs are formed. Also, the lack of testosterone means that no dihydrotestosterone is formed and consequently the external genitalia fail to virilize, resulting in normal female genitalia.\n\n* Without AMH, the Mllerian ducts develop into normal internal female organs (uterus, fallopian tubes, cervix, vagina).\n\n* A baby who is apparently a girl is born and is normal in most anatomic respects except that the child has nonfunctional streak gonads instead of ovaries or testes.\n\n* As girls' ovaries normally produce no important body changes before puberty, a defect of the reproductive system typically remains unsuspected until puberty fails to occur in people with Swyer syndrome.\n\n* They appear to be normal girls and are generally considered so.\n\n* Evaluation of delayed puberty usually reveals elevation of gonadotropins, indicating that the pituitary is providing the signal for puberty but the gonads are failing to respond.\n\n* The next steps of the evaluation usually include checking a karyotype and imaging of the pelvis. The karyotype reveals XY chromosomes and the imaging demonstrates the presence of a uterus but no ovaries (the streak gonads are not usually seen by most imaging).\n\n* Upon diagnosis, estrogen and progesterone therapy is typically commenced, promoting the development of female characteristics.", "source": "wiki" }, "5-alpha-reductase-deficiency": { "id": "5-alpha-reductase-deficiency", "markdown": "![](demdxlogoforhtmls.png)\n\n**5 Alpha Reductase Deficiency \n**\n===================================\n\n \n\n* * *\n\n**Overview**\n\n* 5-alpha-reductase deficiency is an autosomal recessive condition - 46 XY disorder of sexual development which causes reduced conversion of testosterone to dihydrotestosterone (DHT)\n* Patients suffer from impaired virilization during embryogenesis\n* Condition only affects genetic males because DHT has no known role in female development\n\n \n\n \n\n* * *\n\n**Presentation**\n\n* Often presents at birth with female external genitalia however the extent of impaired virilization of the external genitalia is variable, with some subjects having almost complete male genitalia, ambiguous genitalia, or normal female genitalia\n* Condition can become apparent at puberty as the development of non-genital tissues e.g muscle proceed as with a normal male\n\n \n \n\n* * *\n\n**Differentials**\n\n \n\n* 17-beta-hydroxysteroid dehydrogenase 3 deficiency\n* Partial defects in androgen-receptor function\n\n \n\n* * *\n\n**Investigation**\n\n \n\n* Largely a clinical diagnosis, however genetic screening to test for mutation for 5-alpha-reductase 2 enzyme is needed for a definitive diagnosis\n\n \n\n* * *\n\n**Management**\n\n* MDT meeting to discuss patient development given the complexity of gender assignment.", "source": null }, "abo-incompatibility": { "id": "abo-incompatibility", "markdown": "![](demdxlogoforhtmls.png)\n\nABO Incompatibility\n===================\n\n* * *\n\n Definition:\n\n* ABO Incompatibility is a form of haemolytic disease of the newborn starting less than 24 hours of age, which is a complication of pregnancy, resulting when the mother and the fetus have different blood types.\n* The mother will mount an immune response to the foreign red blood cell antigens of the fetus which will result in haemolysis in first born babies.\n* It does not get progressively worse with subsequent pregnancies.\n\nAetiology:\n\n* The group O mother will mount an immune response against the foreign antigens of the fetus being the A or B antigen found on the red blood cells of the fetus through the action of IgG anti-A or B-haemolysin in the blood which can cross the placenta in sensitizing events.\n* This will result in mass destruction of the fetus red blood cells with subsequent consequences. \n \n\nRisk Factors:\n\n* Premature babies\n\nComplications:\n\n* Kernicterus; encephalopathy as a result of unconjugated bilirubin deposition within the basal ganglia and the brain stem nuclei.\n* Late onset anemia\n* Prolonged hyperbilirubinemia\n* Cerebral palsy\n* Neutropenia\n* Thrombocytopenia", "source": null }, "adhd": { "id": "adhd", "markdown": "**ADHD**\n========\n\n![](NHSChoicesLogo.jpg) \n\n* * *\n\n**Overview**\n\n**Attention deficit hyperactivity disorder (ADHD) is a group of behavioural symptoms that include inattentiveness, hyperactivity and impulsiveness.**\n\nSymptoms of ADHD tend to be noticed at an early age and may become more noticeable when a child's circumstances change, such as when they start school. Most cases are diagnosed when children are 6 to 12 years old\n\nThe symptoms of ADHD usually improve with age, but many adults who are diagnosed with the condition at a young age continue to experience problems\n\nPeople with ADHD may also have additional problems, such as sleep and anxiety disorders\n\n### Getting help \n\nMany children go through phases where they're restless or inattentive. This is often completely normal and doesn't necessarily mean they have ADHD\n\nHowever, you should consider raising your concerns with your child's teacher, their school's special educational needs co-ordinator (SENCO) or GP if you think their behaviour may be different to most children their age\n\nIt's also a good idea to speak to your GP if you're an adult and you think you may have ADHD, but you weren't diagnosed with the condition as a child\n\n### What causes ADHD?\n\nThe exact cause of ADHD is unknown, but the condition has been shown to run in families. Research has also identified a number of possible differences in the brains of people with ADHD compared to those who don't have the condition\n\nOther factors that have been suggested as potentially having a role in ADHD include:\n\n* being born prematurely (before the 37th week of pregnancy)\n* having a low birthweight\n* smoking, alcohol or drug abuse during pregnancy\n\nADHD is more common in boys than girls. It's thought that around 2% to 5% of school-aged children may have the condition\n\nADHD can occur in people of any intellectual ability, although it's more common in people with learning difficulties\n\n### How ADHD is treated\n\nAlthough there's no cure for ADHD, it can be managed with appropriate educational support, advice and support for parents and affected children, alongside medication, if necessary\n\nMedication is often the first treatment offered to adults with ADHD, although psychological therapies such as [cognitive behavioural therapy (CBT)](http://www.nhs.uk/conditions/cognitive-behavioural-therapy/pages/introduction.aspx) may also help\n\nRead more about [treating ADHD](http://www.nhs.uk/Conditions/Attention-deficit-hyperactivity-disordePages/Treatment.aspx)\n\n### Living with ADHD\n\nLooking after a child with ADHD can be challenging, but it's important to remember that they can't help their behaviour\n\nSome issues that may arise in day-to-day life include:\n\n* getting your child to sleep at night\n* getting ready for school on time\n* listening to and carrying out instructions\n* being organised\n* social occasions\n* shopping\n\nAdults with ADHD may also find they have similar problems, and some may have issues with drugs, crime and employment\n\nRead about [living with ADHD](http://www.nhs.uk/Conditions/Attention-deficit-hyperactivity-disordePages/LivingwithADHDpage.aspx) for information on ways to cope with these issues\n\n \n\n* * *\n\n**Symptoms**\n\n**The symptoms of attention deficit hyperactivity disorder (ADHD) can be categorised into two types of behavioural problems.**\n\nThese categories are:\n\n* inattentiveness\n* hyperactivity and impulsiveness\n\nMost people with ADHD have problems that fall into both these categories, but this isn't always the case\n\nFor example, some people with the condition may have problems with inattentiveness, but not with hyperactivity or impulsiveness. This form of ADHD is also known as attention deficit disorder (ADD). ADD can sometimes go unnoticed because the symptoms may be less obvious\n\n### Symptoms in children and teenagers\n\nThe symptoms of ADHD in children and teenagers are well defined, and they're usually noticeable before the age of six. They occur in more than one situation, such as at home and at school\n\nThe main signs of each behavioural problem are detailed below\n\n#### Inattentiveness\n\nThe main signs of inattentiveness are:\n\n* having a short attention span and being easily distracted\n* making careless mistakes for example, in schoolwork\n* appearing forgetful or losing things\n* being unable to stick at tasks that are tedious or time-consuming\n* appearing to be unable to listen to or carry out instructions\n* constantly changing activity or task\n* having difficulty organising tasks\n\n#### Hyperactivity and impulsiveness\n\nThe main signs of hyperactivity and impulsiveness are:\n\n* being unable to sit still, especially in calm or quiet surroundings\n* constantly fidgeting\n* being unable to concentrate on tasks\n* excessive physical movement\n* excessive talking\n* being unable to wait their turn\n* acting without thinking\n* interrupting conversations\n* little or no sense of danger\n\nThese symptoms can cause significant problems in a child's life, such as underachievement at school, poor social interaction with other children and adults, and problems with discipline\n\n### Related conditions in children and teenagers\n\nAlthough not always the case, some children may also have signs of other problems or conditions alongside ADHD, such as:\n\n* [**anxiety disorder**](http://www.nhs.uk/conditions/Anxiety/Pages/Introduction.aspx) which causes your child to worry and be nervous much of the time; it may also cause physical symptoms, such as a rapid heartbeat, sweating and dizziness\n* **oppositional defiant disorder (ODD) ** this is defined by negative and disruptive behaviour, particularly towards authority figures, such as parents and teachers\n* **conduct disorder** this often involves a tendency towards highly antisocial behaviour, such as stealing, fighting, vandalism and harming people or animals\n* [**depression**](http://www.nhs.uk/conditions/Depression/Pages/Introduction.aspx)\n* **sleep problems** finding it difficult to get to sleep at night, and having irregular sleeping patterns\n* [**autistic spectrum disorder (ASD)**](http://www.nhs.uk/conditions/autistic-spectrum-disordePages/Introduction.aspx) this affects social interaction, communication, interests and behaviour\n* [**epilepsy**](http://www.nhs.uk/epilepsy) a condition that affects the brain and causes repeated fits or seizures\n* [**Tourette's syndrome**](http://www.nhs.uk/conditions/Tourette-syndrome/Pages/Introduction.aspx) a condition of the nervous system, characterised by a combination of involuntary noises and movements called [tics](http://www.nhs.uk/Conditions/Tics/Pages/Introduction.aspx)\n* **learning difficulties ** such as [dyslexia](http://www.nhs.uk/Conditions/Dyslexia/Pages/Introduction.aspx)\n\n### Symptoms in adults\n\nIn adults, the symptoms of ADHD are more difficult to define. This is largely due to a lack of research into adults with ADHD\n\nADHD is a developmental disorder; it's believed that it can't develop in adults without it first appearing during childhood. But it's known that symptoms of ADHD often persist from childhood into a person's teenage years, and then adulthood\n\nAny additional problems or conditions experienced by children with ADHD, such as depression or dyslexia, may also continue into adulthood\n\nBy the age of 25, an estimated 15% of people diagnosed with ADHD as children still have a full range of symptoms, and 65% still have some symptoms that affect their daily lives\n\nThe symptoms in children and teenagers, which are listed above, is sometimes also applied to adults with possible ADHD. But some specialists say that the way in which inattentiveness, hyperactivity and impulsiveness affect adults can be very different from the way they affect children\n\nFor example, hyperactivity tends to decrease in adults, while inattentiveness tends to get worse as the pressure of adult life increases. Adult symptoms of ADHD also tend to be far more subtle than childhood symptoms\n\nSome specialists have suggested the following list of symptoms associated with ADHD in adults:\n\n* carelessness and lack of attention to detail\n* continually starting new tasks before finishing old ones\n* poor organisational skills\n* inability to focus or prioritise\n* continually losing or misplacing things\n* forgetfulness\n* restlessness and edginess\n* difficulty keeping quiet and speaking out of turn\n* blurting out responses and often interrupting others\n* mood swings, irritability and a quick temper\n* inability to deal with stress\n* extreme impatience\n* taking risks in activities, often with little or no regard for personal safety or the safety of others for example, driving dangerously\n\n### Additional problems in adults with ADHD\n\nAs with ADHD in children and teenagers, ADHD in adults can occur alongside several related problems or conditions\n\nOne of the most common conditions is depression. Other conditions that adults may have alongside ADHD include:\n\n* [**personality disorders**](http://www.nhs.uk/Conditions/Personality-disordePages/Definition.aspx) conditions in which an individual differs significantly from an average person, in terms of how they think, perceive, feel or relate to others\n* [**bipolar disorder**](http://www.nhs.uk/conditions/Bipolar-disordePages/Introduction.aspx) a condition that affects your moods, which can swing from one extreme to another\n* [**obsessive-compulsive disorder (OCD)**](http://www.nhs.uk/conditions/Obsessive-compulsive-disordePages/Introduction.aspx) a condition that causes obsessive thoughts and compulsive behaviour\n\nThe behavioural problems associated with ADHD can also cause problems such as difficulties with relationships, social interaction, drugs and crime. Some adults with ADHD find it hard to find and stay in a job\n\n \n\n* * *\n\n**Causes**\n\n**The exact cause of attention deficit hyperactivity disorder (ADHD) isn't fully understood, although a combination of factors is thought to be responsible.**\n\n### Genetics\n\nADHD tends to run in families and, in most cases, it's thought the genes you inherit from your parents are a significant factor in developing the condition\n\nResearch shows that both parents and siblings of a child with ADHD are four to five times more likely to have ADHD themselves\n\nHowever, the way ADHD is inherited is likely to be complex and isn't thought to be related to a single genetic fault\n\n### Brain function and structure\n\nResearch has identified a number of possible differences in the brains of people with ADHD compared to those who don't have the condition, although the exact significance of these isn't clear\n\nFor example, studies involving brain scans have suggested that certain areas of the brain may be smaller in people with ADHD, whereas other areas may be larger\n\nResearch has also shown that the brain may take an average of two to three years longer to mature in children with ADHD, compared to children who don't have the condition\n\nOther studies have suggested that people with ADHD may have an imbalance in the level of neurotransmitters in the brain, or that these chemicals may not work properly\n\n### Other possible causes\n\nVarious other causes have also been suggested as playing a role in the development of ADHD, including:\n\n* being born prematurely (before the 37th week of pregnancy)\n* having a low birthweight\n* brain damage either in the womb or in the first few years of life\n* drinking alcohol, smoking or misusing drugs while pregnant\n* exposure to high levels of toxic lead at a young age\n\nHowever, the evidence for many of these factors is inconclusive, and more research is needed to determine if they contribute to ADHD\n\n \n\n* * *\n\n**Diagnosis**\n\n**If you think that you or your child may have attention deficit hyperactivity disorder (ADHD), you might want to consider speaking to your GP about it.**\n\nIf you're worried about your child, it may help to speak to their teachers before seeing your GP, to find out if they have any concerns about your child's behaviour\n\nYour GP can't formally diagnose ADHD, but they can discuss your concerns with you and refer you for a specialist assessment, if necessary\n\nWhen you see your GP, they may ask you:\n\n* about your symptoms or those of your child\n* when these symptoms started\n* where the symptoms occur for example, at home or in school\n* whether the symptoms affect your or your child's day-to-day life for example, if they make socialising difficult\n* if there have been any recent significant events in your life or your child's, such as a death or divorce in the family\n* if there's a family history of ADHD\n* about any other problems or symptoms of different health conditions you or your child may have\n\n### Next steps\n\nIf your GP thinks your child may have ADHD, they may first suggest a period of \"watchful waiting\" lasting around 10 weeks to see if your child's symptoms improve, stay the same or get worse. They may also suggest starting a parent training or education programme to teach you ways of helping your child (see [treating ADHD](http://www.nhs.uk/Conditions/Attention-deficit-hyperactivity-disordePages/Treatment.aspx) for more information)\n\nIf your child's behaviour doesn't improve, and both you and your GP believe it's seriously affecting their day-to-day life, your GP should refer you and your child to a specialist for a formal assessment (see below)\n\nFor adults with possible ADHD, your GP will assess your symptoms and may refer you for an assessment if:\n\n* you weren't diagnosed with ADHD as a child, but your symptoms began during childhood and have been ongoing since then\n* your symptoms can't be explained by a mental health condition\n* your symptoms have a significant impact on your day-to-day life for example, if you're underachieving at work or find intimate relationships difficult\n\nYou may also be referred to a specialist if you had ADHD as a child or young person, and your symptoms are now causing moderate or severe functional impairment\n\n### Assessment\n\nThere are a number of different specialists that you or your child may be referred to for a formal assessment, including:\n\n* a child or adult psychiatrist\n* a paediatrician (a specialist in children's health)\n* a learning disability specialist, social worker or occupational therapist with expertise in ADHD\n\nWho you're referred to depends on your age and what's available in your local area\n\nThere's no simple test to determine whether you or your child have ADHD, but your specialist can make an accurate diagnosis after a detailed assessment that may include:\n\n* a physical examination, which can help rule out other possible causes for the symptoms\n* a series of interviews with you or your child\n* interviews or reports from other significant people, such as partners, parents and teachers\n\nThe criteria for making a diagnosis of ADHD in children, teenagers and adults are outlined below\n\n### Diagnosis in children and teenagers\n\nDiagnosing ADHD in children depends on a set of strict criteria. To be diagnosed with ADHD, your child must have six or more symptoms of inattentiveness, or six or more symptoms of hyperactivity and impulsiveness\n\nTo be diagnosed with ADHD, your child must also have:\n\n* been displaying symptoms continuously for at least six months\n* started to show symptoms before the age of 12\n* been showing symptoms in at least two different settings for example, at home and at school, to rule out the possibility that the behaviour is just a reaction to certain teachers or parental control\n* symptoms that make their lives considerably more difficult on a social, academic or occupational level\n* symptoms that aren't just part of a developmental disorder or difficult phase, and aren't better accounted for by another condition\n\n### Diagnosis in adults\n\nDiagnosing ADHD in adults is more difficult because there's some disagreement about whether the list of symptoms used to diagnose children and teenagers also applies to adults\n\nIn some cases, an adult may be diagnosed with ADHD if they have five or more symptoms of inattentiveness, or five or more symptoms of hyperactivity and impulsiveness, that are listed in diagnostic criteria for children with ADHD\n\nAs part of your assessment, the specialist will ask about your present symptoms. However, under current diagnostic guidelines, a diagnosis of ADHD in adults can't be confirmed unless your symptoms have been present from childhood\n\nIf you find it difficult to remember whether you had problems as a child, or you weren't diagnosed with ADHD when you were younger, your specialist may wish to see your old school records or talk to your parents, teachers or anyone else who knew you well when you were a child\n\nFor an adult to be diagnosed with ADHD, their symptoms should also have a moderate impact on different areas of their life, such as:\n\n* underachieving at work or in education\n* driving dangerously\n* difficultly making or keeping friends\n* difficulty in relationships with partners\n\nIf your problems are recent and didn't occur regularly in the past, you're not considered to have ADHD. This is because it's currently not thought that ADHD can develop for the first time in adults\n\n \n\n* * *\n\n**Treatment**\n\n**Treatment for attention deficit hyperactivity disorder (ADHD) can help relieve the symptoms and make the condition much less of a problem in day-to-day life.**\n\nADHD can be treated using medication or therapy, but a combination of both is often best\n\nTreatment is usually arranged by a specialist, such as a paediatrician or psychiatrist, although the condition may be monitored by your GP\n\n### Medication\n\nThere are five types of medication licensed for the treatment of ADHD:\n\n* methylphenidate \n* dexamfetamine\n* lisdexamfetamine\n* atomoxetine\n* guanfacine\n\nThese medications aren't a permanent cure for ADHD, but may help someone with the condition concentrate better, be less impulsive, feel calmer, and learn and practise new skills\n\nSome medications need to be taken every day, but some can be taken just on school days. Treatment breaks are occasionally recommended, to assess whether the medication is still needed\n\nIn the UK, all of these medications are licensed for use in children and teenagers. Atomoxetine is also licensed for use in adults who had symptoms of ADHD as children\n\nIf you weren't diagnosed with ADHD until adulthood, your GP and specialist can discuss which medications and therapies are suitable for you\n\nIf you or your child is prescribed one of these medications, you'll probably be given small doses at first, which may then be gradually increased. You or your child will need to see your GP for regular check-ups, to ensure the treatment is working effectively and to check for signs of any side effects or problems\n\nYour specialist will discuss how long you should take your treatment but, in many cases, treatment is continued for as long as it is helping\n\n#### Methylphenidate\n\nMethylphenidate is the most commonly used medication for ADHD. It belongs to a group of medicines called stimulants that work by increasing activity in the brain, particularly in areas that play a part in controlling attention and behaviour\n\nMethylphenidate can be used by teenagers and children with ADHD over the age of six. Although methylphenidate isn't licensed for use in adults, it may be taken under close supervision from your GP and specialist\n\nThe medication can be taken as either immediate-release tablets (small doses taken two to three times a day), or as modified-release tablets (taken once a day in the morning, and they release the dose throughout the day)\n\nCommon side effects of methylphenidate include:\n\n* a small increase in blood pressure and heart rate\n* loss of appetite, which can lead to weight loss or poor weight gain\n* trouble sleeping\n* [headaches](http://www.nhs.uk/conditions/headache/Pages/Introduction.aspx)\n* [stomach aches](http://www.nhs.uk/conditions/stomach-ache-abdominal-pain/Pages/Introduction.aspx)\n* mood swings\n\n#### Dexamfetamine\n\nDexamfetamine is also a stimulant medication, which works in a similar way to methylphenidate by stimulating areas of the brain that play a part in controlling attention and behaviour\n\nDexamfetamine can be used by teenagers and children with ADHD over the age of three. Although it's not licensed for use in adults, it may be taken under close supervision from your GP and specialist\n\nDexamfetamine is usually taken as a tablet once or twice a day, although an oral solution is also available\n\nCommon side effects of dexamfetamine include:\n\n* decreased appetite\n* mood swings\n* agitation and aggression\n* [dizziness](http://www.nhs.uk/conditions/dizziness/pages/introduction.aspx)\n* headaches\n* [diarrhoea](http://www.nhs.uk/Conditions/Diarrhoea/Pages/Introduction.aspx)\n* nausea and vomiting\n\n#### Lisdexamfetamine\n\nLisdexamfetamine is a similar medication to dexamfetamine, and works in the same way\n\nIt can be used by children with ADHD over the age of six if treatment with methylphenidate hasn't helped. You may continue to take it into adulthood if your doctor thinks you're benefitting from treatment\n\nLisdexamfetamine comes in capsule form, which you or your child usually take once a day\n\nCommon side effects of lisdexamfetamine include:\n\n* decreased appetite, which can lead to weight loss or poor weight gain\n* aggression\n* drowsiness\n* dizziness\n* headaches\n* diarrhoea\n* nausea and vomiting\n\n#### Atomoxetine\n\nAtomoxetine works differently to other ADHD medications\n\nIt's known as a selective noradrenaline reuptake inhibitor (SNRI), which means it increases the amount of a chemical in the brain called noradrenaline. This chemical passes messages between brain cells, and increasing the amount can aid concentration and help control impulses\n\nAtomoxetine can be used by teenagers and children over the age of six. It's also licensed for use in adults if symptoms of ADHD are confirmed\n\nAtomoxetine comes in capsule form, which you or your child usually take once or twice a day\n\nCommon side effects of atomoxetine include:\n\n* a small increase in blood pressure and heart rate\n* nausea and vomiting\n* stomach aches\n* trouble sleeping\n* dizziness\n* headaches\n* irritability\n\nAtomoxetine has also been linked to some more serious side effects that it's important to look out for, including suicidal thoughts and liver damage\n\nIf either you or your child begin to feel depressed or suicidal while taking this medication, speak to your doctor\n\n#### Guanfacine\n\nGuanfacine acts on part of the brain to improve attention and it also reduces blood pressure\n\nIt's used for ADHD in teenagers and children if other medicines are unsuitable or ineffective\n\nGuanfacine is usually taken as a tablet once a day, in the morning or evening\n\nCommon side effects include:\n\n* tiredness or fatigue\n* headache\n* abdominal pain\n* dry mouth\n\n### Therapy\n\nAs well as taking medication, different therapies can be useful in treating ADHD in children, teenagers and adults. Therapy is also effective in treating additional problems, such as conduct or anxiety disorders, that may appear with ADHD\n\nSome of the therapies that may be used are outlined below\n\n#### Psychoeducation\n\nPsychoeducation means that you or your child will be encouraged to discuss ADHD and how it affects you. It can help children, teenagers and adults make sense of being diagnosed with ADHD, and can help you to cope and live with the condition\n\n#### Behaviour therapy\n\nBehaviour therapy provides support for carers of children with ADHD, and may involve teachers as well as parents. Behaviour therapy usually involves behaviour management, which uses a system of rewards to encourage your child to try to control their ADHD\n\nIf your child has ADHD, you can identify types of behaviour you want to encourage, such as sitting at the table to eat. Your child is then given some sort of small reward for good behaviour, and removal of a privilege for poor behaviour\n\nFor teachers, behaviour management involves learning how to plan and structure activities, and to praise and encourage children for even very small amounts of progress\n\n#### Parent training and education programmes\n\nIf your child has ADHD, specially tailored parent training and education programmes can help you learn specific ways of talking to your child, and playing and working with them to improve their attention and behaviour\n\nYou may also be offered parent training before your child is formally diagnosed with ADHD\n\nThese programmes are usually arranged in groups of around 10-12 parents. A programme usually consists of 10-16 meetings, which each last up to two hours\n\nThey aim to teach parents and carers about behaviour management (see above), while increasing confidence in your ability to help your child and improve your relationship\n\n#### Social skills training\n\nSocial skills training involves your child taking part in role play situations, and aims to teach them how to behave in social situations by learning how their behaviour affects others\n\n#### Cognitive behavioural therapy (CBT)\n\n[Cognitive behavioural therapy (CBT)](http://www.nhs.uk/conditions/Cognitive-behavioural-therapy/Pages/Introduction.aspx) is a talking therapy that can help you manage your problems by changing the way you think and behave. A CBT therapist would try to change how your child feels about a situation, which would in turn potentially change their behaviour\n\nCBT can be carried out with a therapist individually or in a group\n\n### Other possible treatments\n\nThere are other ways of treating ADHD that some people with the condition find helpful, such as cutting out certain foods and taking supplements. However, there's no strong evidence these work, and they shouldn't be attempted without medical advice\n\n#### Diet\n\nPeople with ADHD should eat a healthy, balanced diet. Don't cut out foods before seeking medical advice\n\nSome people may notice a link between types of food and worsening ADHD symptoms. For example, sugar, food colourings and additives, and caffeine are often blamed for aggravating hyperactivity, and some people believe they have intolerances to wheat or dairy products, which may add to their symptoms\n\nIf this is the case, keep a diary of what you eat and drink, and what behaviour this causes. Discuss this with your GP, who may refer you to a dietitian (a healthcare professional who specialises in nutrition)\n\n#### Supplements\n\nSome studies have suggested that supplements of omega-3 and omega-6 fatty acids may be beneficial in people with ADHD, although the evidence supporting this is very limited\n\nIt's advisable to talk to your GP before using any supplements, because some can react unpredictably with medication or make it less effective\n\nYou should also remember that some supplements shouldn't be taken long term, as they can reach dangerous levels in your body", "source": "nhs" }, "aids-cholangiopathy": { "id": "aids-cholangiopathy", "markdown": "![](demdxlogoforhtmls.png)\n\n**AIDS Cholangiopathy**\n=======================\n\n \n\n* * *\n\nDefinition\n\nAIDS Cholangiopathy is a cholangitis, in the absence of gallstone formation, which occurs in patients with AIDS secondary to immunosuppression. \n\n* * *\n\n****Presentation****\n\n* RUQ pain \n \n* Fever\n* Weight loss\n* Diarrhoaea\n* Increased alkaline phosphatase\n\n \n\n* * *\n\n**Aetiology**\n\nIn many patients, the causative organism is not identified. Typical organisms associated are:\n\n* Cytomegalovirus\n* Herpes simplex virus\n* Crytosporidium parvum\n* Microsporidium\n* Mycobacterium\n\nAIDS cholangiopathy is uncommon in current practice due to the introduction of HAART to treat HIV.\n\nIntroduction of HAART therapy in those who have not commenced therapy may allow for improvement in patients.\n\n* * *\n\n****Pathology****\n\nPatients with low CD4 counts, typically <200 x 106 are usually affected. The pathology typically falls into four categories.\n\n* sclerosing cholangitis and pappilary stenosis\n* sclerosing cholangitis appearance\n* extrahepatic duct stricture with or without intrahepatic disease\n* papillary stenosis\n\n**Investigations**\n\n* FBC (high WCC, especially neutrophils), LFTS.\n* Blood cultures\n* Ultrasound bile duct dilatation, stones in GB, biliary sludge.\n* ERCP diagnostic\n* MRCP\n\n* * *", "source": null }, "aids-neuropathy": { "id": "aids-neuropathy", "markdown": "![](demdxlogoforhtmls.png)\n\n**AIDS Neuropathy**\n===================\n\n* * *\n\n**Overview**\n\n* Common in HIV\n \n* Wide-spectrum including peripheral and autonomic neuropathy as well as neuromuscular conditions\n \n* Specific diseases include: \n o Distal symmetric polyneuropathy (most common) \n o Acquired inflammatory demyelinating polyradiculoneuropathy (acute/chronic) \n o Autonomic neuropathy \n o Progressive polyradiculopathy / CMV Neuropathy \n o Mononeuropathy multiplex \n o Lumbosacral polyradiculopathy (cauda equina syndrome) \n o VZV radiculitis \n o Sensory ganglioneuritis\n \n* Causes: \n o Autoimmue mechanisms induce inflammatory injury e.g. macrophage and T cell infiltration of peripheral nerves and dorsal root ganglia \n o Nutritional deficits (eg, vitamin B-12) due to enteropathies and malabsorption caused by intestinal HIV, CMV, or HSV infection \n o Co-infection with CMV, HSV, VZC, MAC, Syphillis directly causing neuromuscular complications\n \n* Overall incidence has declined with antiretroviral use (likelihood correlates with viral load and CD4+ counts) \n \n\n* * *\n\n**Presentation**\n\n* Distal sensorimotor polyneuropathy (DSPN) is the most common presentation \n o Usually late in illness course \n o Painful, tingling \n o Bilateral, stocking distribution gradually spreads proximally in lower limb extremities \n o Sensory loss across all sensory modalities\n \n* Acute (Guillan Barre syndrome) or chronic inflammatory demyelinating polyradiculoneuropathy (CDIP) \n o Common at seroconversion or initial disease manifestation \n o Autoimmune dysfunction \n o Symmetric, proximal and distal muscle weakness with areflexia\n \n* Progressive polyradiculopathy \n o Typically CMV and other herpes virus infections \n o Cauda equinalike picture\n \n* subacute onset of lower extremity weakness \n o Most patients will have prior evidence of CMV infection diagnosis elsewhere\n \n* Mononeuropathy multiplex \n o Early: Inflammatory response \n o Late: Usually CMV infection \n o Asymmetric, painful sensorimotor polyneuropathy affecting multiple nerves, often in a stepwise progression\n \n* Autonomic neuropathy \n o sexual dysfunction, diarrhoea, bladder dysfunction, orthostatic hypotension, anhidrosis / hyperhidrosis\n \n* Varicella zoster neuropathy \n o Spread of the reactivated virus from sensory ganglia to adjacent neural structures \n o Cranial: optic neuropathy and facial palsy (Ramsay-Hunt syndrome). \n o Peripheral nerve palsies: pain, weakness, and numbness in the distribution of a nerve root\n \n* Sensory ganglioneuritis \n o Rare \n o Acute phase \n o Widespread, non-length dependent sensory loss, ataxia, and areflexia\n \n\n* * *\n\n**Differentials**\n\n* Acquired demyelinating polyradiculoneuropathy (GBS of other origin)\n \n* Vasculitic neuropathy\n \n* Hep C\n \n* Vit D deficiency\n \n* Folate\n \n* Hypothyroidism\n \n* Diabetes neuropathy\n \n* Myeloma\n \n* Uraemic neuropathy\n \n\n* * *\n\n**Investigations**\n\n* Mainly clinical diagnosis\n \n* Screen for alternative diagnoses (e.g. significant weakness, asymmetry of signs)\n \n* Electromyelography \n o Electrodiagnostic studies show a sensorimotor polyneuropathy, which is predominantly axonal\n \n* Nerve Conduction Studies \n o Distinguishing DSPN from acquired inflammatory demyelinating neuropathy\n \n* Bloods to screen for other causes (usually unremarkable in HIV neuropathy) \n o Hepatitis C antibody \n o Vitamin B12 and folate levels \n o TSH assay \n o Blood glucose \n o Renal profile \n o SPEP and immunoelectrophoresis\n \n* LP \n o Not routine only if suspicious of CMV, polyradiculopathy or lymphoma \n o CMV-induced polyradiculopathy high WCC - polymorphonuclear leukocytes (PMN) \n o GBS / CIDP elevated CSF protein \n o PCR for CMV or VZV\n \n* MRI \n o Lumbosacral spine to exclude compression of the cauda equine\n \n* Autonomic dysfunction \n o Cardiovascular reflex functions, blood pressure (inc. postural) etc.\n \n* Biopsy skin, nerve - rarely\n \n\n* * *\n\n**Management**\n\n* Optimum HIV management with anti-retrovirals\n \n* Treatment of painful dysthaesias \n o Gabapentin \n o Topical agents - lidocaine, capsaicin \n o Opiates - breakthrough pain\n \n* Demyelinating polyradiculopathy \n o As per non-HIV GBS: IVIg, Plasmapharesis\n \n* Autonomic\n \n* Pressors: fludrocortisone, midodrine\n \n* Treat infectious cause \n o E.g. Intravenous ganciclovir (CMV) or acyclovir (VZV)", "source": null },
}
submitted by chrisphillers to learnjavascript [link] [comments]


2020.03.22 17:45 brownbear454 Atypical Presentations for COVID-19. The story of my hospitals first case.

District general hospital serving a population of about 175,000
33y/o male presents with sudden onset headache, photophobia, and fever. smokes 5-10/day lives with partner. no PMH other than obesity. no recent travel no sick contacts
Bloods all normal
Impression was viral meningitis, started on treatment.
Admitted and isolated, has an LP
LP results WCC: 0 (can't remember the rest but all within normal ranged). Awaiting CSF and blood cultures. Plan was to continue treatment until cultures back. However, patient is persistently spiking temperatures to 39-40 Celsius
By now we're about day 3 of admission with no staff members taking aerosol precautions. I get reassigned from medical admissions unit to a medical ward. This guy gets transferred over to said ward but hasn't been seen yet that morning so I add him to my ward round list.
Patient no longer has any symptoms of meningitis other than fever. No cough, coryzal symptoms, no urinary or bowel symptoms.
As LP is normal I decide to call this 'fever of unknown origin' so I elect to start aerosol precautions and COVID swab.
CXR, urine dip not done yet, but both came back as normal.
48 hours later he became our hospitals first confirmed COVID-19 case.
Pt is well and is expected to home to self isolate.
We're all scratching our heads here but I suppose it is a viral meningitis. I haven't seen anything written about COVID related meningitis but even so if I see any more ?meningitis cases I'm swabbing them.
submitted by brownbear454 to medicine [link] [comments]


2020.01.06 22:30 Throw-987654321 Viral Meningitis (HSV-2) - Long Recovery

My partner (27F, 65kg, 170cm, athletically fit and otherwise in good health with no prior medical history, doesn't drink, smoke or use recreational drugs) was hospitalised with viral meningitis (HSV-2) 8 months ago. The usual symptoms - severe headache, neck pain, chills, and so on. Doctor Google suspected meningitis and suggested a trip to the hospital post-haste so off we went and after many long hours waiting in A&E things started to move quickly once meningitis was suspected. Lumbar puncture confirmed meningitis, with HSV-2 present in CSF. IV aciclovir was administered and three days post-admission in the infectious diseases ward we were discharged. She was better than when admitted, but not much, with many of the symptoms still present. No follow up care was suggested and the doctors seemed confident she would be back on her feet in a matter of days or weeks. 'Viral meningitis is pretty benign', the story went.
Unfortunately, that has not been the case. 8 months on and she is doing better - but about a country mile away from where she was before. Headache and fatigue persist on a daily basis, which has had an immense effect on her quality of life. She returned to work some time ago but the situation quickly became untenable - codeine and paracetamol + ibuprofen cocktails just to get through the day, and she was still falling asleep at her desk, occasionally had difficulty focusing on her monitor (blurriness), bad headaches and was locking herself in the bathroom on her lunch break to sleep on the floor. She was put back on medical leave. Her progress hasn't been linear - there have been weeks (about 6 weeks ago) where she has felt that she has improved to the extent maybe she could try to do some light exercise, only for matters to deteriorate before that could come to fruition. Recently she has been napping for 3-4 hours per day despite 10 hours of sleep over night. Headache frequency and the need for meds has increased (she has been trying to ration these to prevent painkiller rebound headaches from developing).
We have both read anecdotal reports that viral meningitis symptoms can persist for some for up to a year. Frankly, if we could be confident that this would all be over in the remaining 4 months, at this point that would be good news - but there is a lot of ground left to cover to a full recovery. I think we are both looking for the light at the end of the tunnel. In terms of medical support I note that the doctors just keep sending her home with a script for codeine, OTC painkillers and bed rest, and was curious if this subreddit is able to comment and perhaps had some more proactive ideas.
Some questions:
  1. Can anyone with experience treating this comment on her progress, i.e. if this is 'normal' and we should stay the course or if we should be worried or doing something or seeing someone?
  2. Should we ask her GP for a referral to a specialist, like a neurologist? If so, what type?
  3. A couple of weeks ago I found this article in a medical journal (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139051/) suggesting (with limitations) that steroids may be an effective treatment for post-viral meningitis headaches. The authors note that their study is imperfect and my partner and I are both risk-averse, educated professionals not keen on haphazard medical experimentation, so while we have discussed this avenue there has been some trepidation. This morning I came across this Redditors post (https://www.reddit.com/Meningitishelp/comments/eegalp/recovering_from_viral_meningitis/) mentioning that prednisone cured him of all of his viral meningitis related ills. We happen to have a full course of prednisone at home and in general my understanding is that steroids are relatively safe (we don't want to do anything here that could make the situation *worse*) and that this may be worth a shot if our understanding that it is unlikely to cause harm is correct. Any thoughts on this would be appreciated.
Any other thoughts or comments from the community greatly appreciated. Thanks for reading.
submitted by Throw-987654321 to AskDocs [link] [comments]


2019.12.28 01:39 c_o_n_a_r_t No-Brainer

Not gonna lie—I took one look at the scene and vomited all over my uniform. From what I could tell, among my fellow officers, my reaction was the most extreme. But it was evident in their postures, hushed breaths, and bleak expressions that they were equally disgusted in their own ways. Eventually though, my mind and stomach caught up to reality and I was able to look at the spectacle in all its glory.
On top of a tree trunk near the Robinswood Park playground—just a few feet from the swing set—rested a completely intact human brain.
Detective Kenzie—who had been first on the scene, shuffled over to me. “Just like our caller said.” He muttered, shaking his head. “Jesus fuck, man.”
Sergeant Matthews, whose shoes were sprayed a little by my breakfast, chimed in. “It doesn’t look like it’s been out here long. Still pink—at least in the grooves.”
“Just in time for the kiddos to get out of school.” Officer Jordan chuckled grimly.
“So what now?” Kenzie asked. “Paramedics?”
“It’s outside the body, son.” Matthews replied.
We paused there for a second as everything sunk in. Rain had started to sprinkle, and with it a red stream trickled down the side of the tree stump.
“Fuck!” Kenzie held his arm over his mouth. “The thing’s fucking bleeding!”
I remembered something from high school biology. “That’s not blood.” I corrected through sour breath. “That’s CSF—cerebrospinal fluid. Looks like it didn’t drain all the way before getting put there.”
“Handled pretty carefully, then.” Jordan added.
“Yeah. Or just really really fresh.”
Forensics arrived shortly thereafter, and we were more than happy to let them get on with their work. Naturally, I was put on the case along with Kenzie—who was my partner at the time. Though we didn’t make a whole lot of headway in the following few days, we were able to extract some information from the crime scene photos.
The brain on top wasn’t the only weird thing about the tree stump. Upon closer examination, it was covered in shallow, unnatural scratches. I’d like to say they formed symbols, but they were so tightly packed into the surface that they were pretty undefined. The markings bled into each other, forming a network of lines, circles, and odd geometrical patterns. Even with Google’s help, we couldn’t determine what any of them meant. They were just indecipherable.
Kenzie and I were way over our heads. After work, we’d go for drinks and inevitably wax philosophical about the whole thing. Our discussions always started out about our families or the neighborhood or other cases—but they all inevitably came back to the brain. I can’t remember all of them, but the one from last night is still pretty fresh in my head. Kenzie had downed a little whiskey and I was finishing off the second of five beers I’d have that night.
“Listen, I know we’ve beat this thing like a dead fucking horse,” he started, “but can we just sit back for a second and admire the whole brain situation?”
“What’s there to admire?” I asked.
Kenzie leaned forward. “There hasn’t been a murder around here for the past what—two years? No missing persons, no kidnappings... I mean yeah, a few assaults here and there but that’s just natural.”
“Mhm.”
“And then just...” he laughed nervously, “like... when I wanted to become a cop, I wasn’t exactly expecting to see the pretty side of town. But you gotta admit that there’s almost a cosmic air about it. Like things have just been going too well here and some thing’s come along to compensate. I mean, there are sickos out there, you know, but this is fucking unholy. Like actually fucking unholy.”
“I think you’re reading too much into it.”
“Maybe, but what else can I do?”
Kenzie flagged the bartender and got another glass of whiskey. He gulped it down in barely a second.
He turned to me then, a weird expression on his face that I couldn’t quite pin down. “You ever feel... like when you see it in the photos and stuff... like it’s just...”
He turned away and cut himself off. “Not familiar but... I dunno. Something close to it.”
I made a mental note to cut him off from the whiskey and tried to decipher his question. “You mean about the brain?” I replied, chuckling.
“I dunno man—it’s just a weird thing. Like you know when you see someone you knew as a kid and you just barely recognize them?”
“Uh huh.”
He folded his arms, obviously struggling to collect his thoughts. “Maybe I’ve been looking at the pictures too much. I just can’t shake this kind of... crawly feeling it gives me.”
“Well it’s a disembodied brain, dude.”
Kenzie grinned. “Forget it, man. It’s stupid—I feel stupid for bringing it up.”
“Nah, I don’t mean to cut you off or trivialize it. It just hits me differently is all. Like—obviously it’s gory and the symbols around it are fucking bizarre. But it’s like serial killer crazy—I’d even say it’s tamer than some of like... Bundy’s fucked up stuff.”
“That’s not saying much.”
“I seriously think we’re gonna find a crazy but perfectly ordinary motherfucker at the end of this who’s done this kind of thing all over the country.”
Kenzie pointed at me, glass in hand. “The ‘No-Brainer’.” He announced dramatically.
I laughed. “Jesus, dude!”
“That’s what they’ll call him, man!”
“Too fucking soon.”
“It’s a good serial killer name though, right?”
“I mean, yeah.” I took a swig from my third bottle. “Yeah, it’s got a ring to it, that’s for sure.”
Forensics arranged a meeting at 9:00am today with our entire department. I grabbed a donut before taking a seat next to Kenzie—who was visibly drained from last night. Jordan joined us shortly thereafter, half a donut in his mouth.
“Hey,” he muffled, “either of you know what this is about?”
“The only thing it could be about.” Kenzie replied.
“I mean, I assume. Think they’ve found the shithead?”
“Let’s hope.”
Jordan perked up a little and pointed to the door. Sergeant Matthews had just entered the room. I think that was the first time I’d ever seen Matthews visibly shaken. As much as he tried to force a calm demeanor, there was no hiding his red eyes and shaking hands.
Jordan sighed. “Well that’s not a good sign.”
“Wonder if they found another one.” I muttered.
A woman I’d never seen at the station before followed Matthews in, but halted before stepping through the doorway. She had a clean suit on and an overall aloof demeanor; her look just screamed federal agent. I also could’ve sworn she glanced at us right before stopping. With an oddly neutral voice, the woman hollered over to Matthews, who paced back over to her with unusual urgency. The two leaned toward each other and exchanged a few words before Matthews looked over at us. I was able to make out Matthews telling the suit “I’m sorry—I’ll take care of it” before turning over to Jordan, Kenzie and I.
“Detective Kenzie!” Matthews beckoned. “This is Agent Leibowitz—would you mind following her out for a second?”
Kenzie gave me a confused look and rose steadily from his seat. “Sure—am I in trouble?” He asked.
“No, you’re not in trouble.” Leibowitz replied. “We just need your help with some records.”
Bullshit. Kenzie knew it too, but he followed Leibowitz out of the conference room anyway. He gave me one last concerned glance before Matthews closed the door behind him.
The meeting began shortly thereafter. A forensics department guy, Yu, came in and stood at the front of the room—noticeably jittering his hands. “Morning, everyone.” He muttered. “Sorry for such an early meeting, but we got word from up top to take care of this as soon as possible. For the few guys here that don’t know me, I’m Harold Yu—I work in forensics downstairs. Of course, most recently, I’ve been busy on our Robinswood case.
“Now, as your fellow officers can tell you, we haven’t been making much progress figuring out how anyone could’ve done this. Since we didn’t have a body or any other physical clues to accompany the brain, we moved pretty quickly into DNA analysis. The tests found two distinct signatures on the brain—so, one for a killer and one for a victim. When we tried to find a match for either of them, though, we couldn’t find any—not from missing persons or criminal records or anything.
“So... after we ran through those local records, we started looking state-wide. Again, no luck. We were trying to figure out what to do with our “brain doe” when one of our seniors had the idea to run it through the officer database. He thought this could be a gang-related thing—maybe like a warning. Wanted to check if any state patrol recently went missing on duty.
“To cut to the chase, we found a match.”
The door creaked open and I noticed Leibowitz re-enter the room. Seeing her sent a cold twinge running down my back, and I realized Something was very, very wrong.
“Wait, wait,” Jordan blurted, “you think Kenzie did it?”
“You don’t understand—“
“No no no—he wouldn’t fucking cut a guy’s brain out. Are you shitting me?”
“Hey!” Matthews hollered. “Son, not the time!”
Jordan’s leg was shaking so bad I could feel the ground next to him vibrate. He gave an offended grunt and folded his arms as Yu continued.
“You don’t understand me.” Yu continued. “Now obviously our gut reaction was to investigate Kenzie as a suspect, but we had kind of a nagging suspicion. We collected more samples, this time tissue from the inside of the cortex—from the brain cells themselves. The samples all matched only one of the DNA strains from our initial test.
“Evidently, it was also the one we matched to Kenzie.”
My stomach nearly jumped up my throat. “Wait...” Jordan interrupted again, “wait, what the fuck do you mean?”
“He means it’s Kenzie’s brain, son.” Matthews rasped.
“He’s in the other fucking room!” Jordan shouted. “He was sitting right here! What the fuck do you mean it’s his?”
“Listen.” Yu tried to calm Jordan down. “We checked these tests to death. We dumped hours into this and honestly still didn’t believe it until we found something else.”
Yu reached into a bag by his side and pulled out some papers. “About a year ago, Kenzie had surgery to mitigate his seizures.” He explained. “Corpus callosum surgery—a little chunk of the nerves connecting the two halves of his head got removed.”
He slid a brain scan from a thick folder and held it up. “We checked our brain. Exactly the same region had been removed. Not roughly. Exactly.”
The room was still. Jordan’s face was as indignant as before, but now completely frozen. I myself felt ready to throw up. Matthews’ gaze was firmly fixed on the floor. Even Yu seemed suddenly sobered, setting Kenzie’s scan back on the desk face-down.
Eventually, a set of slow footsteps broke the silence. Leibowitz calmly and steadily walked up to the front of the room and cleared her throat.
“I understand this must be confusing.” She announced. “Unfortunately, this is about as much information as we can afford you. Kenzie will remain here until we can escort him to a safer location—for his own protection. As for you all, the case is no longer within your jurisdiction. We’ll be confiscating all evidence, records, and documents relating to this case and expect you to help us keep it within the walls of this station.”
She turned to the door and motioned two other agents in—both of whom carried large briefcases. “We appreciate all the work you’ve done so far.” Leibowitz thanked us flatly before strolling out of the room.
The next few hours in that conference room were a complete flurry. Papers packed full of legalese were shoved in my face and I was forced to sign every last one. Words like “forbidden”, “incident”, “penalty”, and “discretion” danced before my eyes in contexts I’d never seen before. People in suits entered and left the station—some waving badges that didn’t belong to any organization I recognized. Instinctively, though, I knew those badges carried authority far above mine. Not everyone was compliant at first. Jordan outright refused to sign anything that was put in front of him. But after he was briefly taken outside by agents for “a word”, he kept his head down and flew through the forms.
As I write this from my phone, we have Kenzie under observation still—tucked away in the most interior room of our station. Evidently it’s taking the agents a little longer to escort him than expected, but it’s probably only a matter of time before he’s whisked away. Until then, none of us are allowed in or out of the station. Oddly enough, though, they didn’t guard the surveillance room very well.
I snuck in when they weren’t looking. It was pretty easy to find which screen was for Kenzie’s room, but not because I could spot Kenzie.
It’s because all the cameras were working except for just one—a small monitor in the middle that was completely black. And the sound coming from it was nothing but muffled sloshing and the faint chirping of birds.
submitted by c_o_n_a_r_t to nosleep [link] [comments]


2019.12.01 07:46 akurjata The Moving To/Visiting/Wondering About/Best Of Prince George Mega-Thread

The Moving To/Visiting/Wondering About/Best Of Prince George Mega-Thread
The most frequently asked question in this subreddit is some variation of “I’m thinking of moving to Prince George, what is it like/which neighbourhood should I choose/is there anything to do?”
In an effort to cut down on these posts AND provide a helpful bunch of information, I’m starting this thread for tips/tricks/recommendations/warnings.
Here’s the idea: I’m going to put a few links below, as well as some topics that might be useful but I don’t personally have the answers to (such as resources for finding a place to rent).
I’m also going to start a few threads for top-level topics, such as neighbourhoods and best ofs, and people can post their responses there.
You can add your own answers/advice as top-level comments. Please try and search before commenting in order to avoid duplicates, and to make things are easy to search and organize.

About Prince George

Canada Games Plaza
The greater Prince George area has a population of about 86,600 people but, as the largest community for hundreds of kilometers in all directions, it tends to punch above its weight in many respects because you aren't driving into a nearby metro area for an evening's entertainment. It is a government, service and healthcare hub, home to a college and university, and has a diversified enough economy that it isn't wholly dependent on any one or two industries, though forestry remains a vital driver along with mining, oil and gas and energy activity in other northern communities. It is at the confluence of the Fraser and Nechako Rivers and has many outdoor recreation opportunities.
Prince George is built on the unceded territory of the Lheidli T'enneh First Nation, who are frequently partners with the city on major initiatives, including the building of the University of Northern British Columbia and hosting of the 2015 Canada Winter Games.
Learn more on the Prince George, British Columbia Wikipedia page, the city's official website and Statistics Canada.

Moving to Prince George

Downtown Prince George/City of Prince George
Move Up Prince George is an official city resource aimed at helping people considering the move to Prince George. Some of its resources include:
Utilities

Existing Moving To/Rental Threads:

Education

Healthcare:

Things to Do

Pidherny Bike Trails/Tourism PG
Tourism Prince George is pretty comprehensive. It is organized as follows:
Restaurants
There’s a fairly robust restaurant scene. A couple of good resources:
Events

Transportation

Like most mid-sized Canadian communities that boomed in the mid-20th century, Prince George is a fairly car-centric city. But with the arrival of more and more post-secondary students, people are able to get around without their own wheels. Here is a previous discussion about cars and transit in the city.
Getting Around
u/InfiNorth's Transit Map of Northern B.C.
There are two taxi companies: Prince George Taxi and Emerald Taxi. Both have online booking and apps
Getting To/From

Community Groups

Mr. PG is a lumberjack and an ally
Sports and Recreation:
LGBTQ+:
Religious:
Indigenous:
Cultural Associations:

Local Government


This is actually our coat of arms

Media & News

Air Quality

Back in the day, Prince George was a much more mill-based city than it is now, but the reputation of a certain odour… lingers. You can still smell the industrial activity in certain parts of town and under certain circumstances, but there have been dramatic improvements in industry standards in recent decades. If you’d like to learn more you can read up at the Prince George Air Quality Improvement Roundtable or jump to the official thread discussing it.

Other online communities:

There are plenty of Prince George-centric Facebook groups. Some of the most popular include:
In order to differentiate from the young royal on Twitter and Instagram, common hashtags are:

Other helpful links stolen from Vancouver):

submitted by akurjata to princegeorge [link] [comments]


2019.09.22 02:56 brookelikesbooks Sophomore looking for advice on ECs (& summer programs)

Hi guys! I'm a (female) sophomore looking for some pointers on how to find EC opportunities/develop my ECs. I'm doing well academically, but I'm a little late in starting meaningful ECs as I didn't realize their importance until recently. This meant I didn't get to explore and try things out freshman year- that's why I'm trying to figure it out now! I've never been particularly drawn to one subject mattefield, and I'm not really into sports/music/etc. I'm interested in politics/government and I write a lot in my free time, but I only recently started exploring these interests. I'm also interested in business, but I haven't done anything to explore that so far.
Freshman year I did pretty generic activities:
-Key Club (50+ hours of community service)
-Frosh cheerleading team (10 hours a week)
-Taking extra gymnastics/cheer classes (2-3 times a week)
-Volunteering at a local animal shelter (2 hours every weekend)
-CSF (California Scholarship Federation)
I've been continuing these activities this year so far with a couple differences; I'm now on the JV cheer team (time commitment is now about 15 hours a week) and I haven't decided if I want to do Key Club again since it's such a generic club. I enjoy doing community service, but lots of people have told me I should just devote the time to a specific cause rather than Key Club. I don't think I'm going to do cheer juniosenior year because it takes up a lot of my time and I'm not super passionate about it- I mainly joined because I did cheer for a year when I was younger, and it's fulfilling my school's two year PE requirement.
Additional activities I've started this year so far:
-Started my own blog over summer (I only have about 10 followers, and I haven't focused in on a specific topic to write about, but I do post consistently)
-YMCA Youth and Government - model legislature and court where we debate bills and model the government (meets weekly, but there's a couple weekend long conferences with other delegations)
-Spanish National Honors Society - (basically a Spanish club but had requirements to get in: being in Spanish 3 or above, all As/Bs in Spanish courses)
-Member of the editorial staff for a teen literary magazine (it's called Polyphony Lit and anyone can apply for a position, you should check it out!) - I'm the lowest rank of staff as a new member, so I just read submissions and offer feedback/my opinion
-Member of my school's yearbook staff (counts as a class period/elective)- I'm mainly going to be writing copies, but I'll also be designing some pages
-Member of a local leadership/volunteer committee that has monthly meetings and various events with the goal of helping underprivileged families in our area
-Peer tutoring in my school's history center once or twice a week at lunch (mainly in the subject of AP Human Geo since that's the history-related class I took last year)
I've definitely upped my game since last year and I'm diving deeper into some interests, but I go to a fairly competitive public high school where everyone seems to be involved in tons of amazing organizations/clubs/activities; most of these activities are somewhat competitive and it's difficult to get leadership positions or get involved unless you're populafriends with the current leaders in the club/activity.
Side note- I wanted to try out for my school's mock trial team, but I decided against it because it was a huge time commitment and the competitions would have conflicted with Youth and Government events. As far as activities I'm still considering getting involved in, here's a few (please offer your opinions on what would be good for me to try!):
-School clubs more tailored to my interests -my school has around 80 active clubs so it's overwhelming for me to figure out to join. The clubs I'm currently considering are JSA, FBLA, Amnesty International, the school literary magazine club, National English Honors Society, Speech & Debate, UNA-USA, Young Entrepreneurs Society, and Young Investors Society. Obviously I am not going to join all of these, but I'm torn on which ones to join since they all relate to my current main interests. I want to figure out which ones will be the best fit for me so I can commit to them for the rest of high school, since I'll already be a year late in joining/being able to work my way up into a potential officer position.
-Company program- My school partners with Junior Achievement to help any kids interested in starting their own companies. I think this is technically a club, but it's sponsored by our career education office so it's a little bit different and more of a serious commitment than a club. However, I don't really have any company ideas... the advisor said lots of people come into it without ideas, but I'm not sure if I would be able to come up with a genuinely good business idea even with brainstorming.
-Internship- I contacted a county government official that's kind of a family friend, and he said I could intern with him whenever I have the time. I definitely want to take this opportunity, but I can't until cheer season is over.
-Dual enrollment classes at my local community college- A lot of kids at my high school do this, and I thought it sounded really cool since you can get college credit and it's a way to take classes in topics that interest me/that aren't offered at school.
-Summer programs- it's pretty far in advance, but I was wondering if summer programs would be worth it for someone like me who doesn't have a specific career focus/direction. I know a lot of the most prestigious programs are for juniors, so that's a limitation; also, I've heard of a few prestigious writing programs (Iowa, Kenyon, etc.) but I don't think I'm at the level of writing that those programs expect. I mainly write for fun- I've had a couple of poems win local-ish contests, but nothing major. I also was thinking a leadership seminaconference/program might be a good idea as I can be kind of shy/awkward with people and would like to improve my public speaking and leadership skills. I know it's important to continue exploring your interests in the summer, and I figured I would start looking for opportunities early since I'm very indecisive and will need the time to figure out the logistics.
I'm sorry for rambling, I know this was really long. Basically, I've read about all these people having unique and intriguing extracurriculars that they're passionate about with lots of leadership roles, and I would love some advice on how I can get on the right path to do something similar. I haven't ever had a leadership role in anything, and I would like to find some activities that I can really enjoy and get super involved in/get leadership roles in. I know it probably sounds like I've joined a lot of random activities and am spreading myself a little thin already, but it's just because I want to explore and I'm not sure how much is too much/what I should try.
Thank you in advance for any advice you may have!
submitted by brookelikesbooks to ApplyingToCollege [link] [comments]


2019.09.19 17:19 0xTT Information Security Compliance Specialist in Tacoma, WA (on-site, full-time)

View Description / Apply (Use these links for greater visibility to our recruiters)

Information Security Compliance Specialist

Infoblox
Information Technology Tacoma, Washington
Apply (Use these links for greater visibility to our recruiters)

Description

Infoblox is seeking an Information Security Compliance Specialist to help identify, analyze, and minimize Infoblox’s risk exposure related to processes, systems, and data with a focus on third-party vendor contracts. This position is based in Tacoma, WA, and reports to the Senior Manager of Security Compliance.
The main responsibilities of this Specialist include working with Legal/Privacy and the Business units to document the location of sensitive data and systems and assist with entering them into the system. This work supports key compliance initiatives such as GDPR, CCPA, and state breach notification laws.
This Specialist will lead the implementation of a standardized process of sending security assessments to third party vendors using an automated tool. Risks which are identified will be tracked to resolution and status regularly reported to the corporate risk registry.
At Infoblox, we are taking a fresh and innovative approach to control, analyze, and secure networks by intelligently managing core network services (DNS and DHCP), threat analysis, and security tools. We are currently moving key products to the cloud and working on several privacy and security certifications. You will have the opportunity to drive risk assessments to the next level for a world-wide company.
Responsibilities:
Requirements:
The ideal candidate will possess…
Education:
Perks:
It’s an exciting time to be at Infoblox. We are the market leader in Technology for network control. Our success depends on bright, energetic, talented people who share a passion for excellence in building the next generation of networking technologies—and having fun along the way. Infoblox offers a fast-paced, action-oriented environment. We promote a culture that embraces innovation, change, teamwork, and strong partnerships built through respect and fun. Join the winning Infoblox team—our future looks bright, and so will yours. To check out what it’s like to be a Bloxer click here.
This job may serve as an entry point for an ambitious person who wants to get into information security who currently has experience with internal audit or governance/risk/ compliance. The Infosec team at Infoblox is a dynamic new team which is building out processes based on compliance needs. Audit is an extremely important piece to make this company successful.
Apply Now (Use these links for greater visibility to our recruiters)
submitted by 0xTT to CyberSecurityJobs [link] [comments]


2019.09.19 17:18 0xTT FedRAMP Senior Compliance Analyst in Tacoma, WA (on-site, full-time)

View Description / Apply (Use these links for greater visibility to our recruiters)

FedRAMP Senior Compliance Analyst

Infoblox
Information Technology Tacoma, Washington
Apply (Use these links for greater visibility to our recruiters)

Description

Infoblox is seeking a FedRAMP Compliance Analyst that will assist with the attainment and maintenance of our FedRAMP certification. This position is based in Tacoma, WA, or remotely from a home office in the US.
The main responsibilities of this analyst will include working with Infoblox Engineering and the Business to document risks and improvement plans. Creation and maintenance of FedRAMP required documents utilizing Federal templates.
At Infoblox we are taking a fresh and innovative approach at controlling, analyzing, and securing networks by intelligently managing core network services (DNS and DHCP).
Responsibilities:
Requirements:
The ideal candidate will possess…
Education:
Perks:
It’s an exciting time to be at Infoblox. We are the market leader in technology for network control. Our success depends on bright, energetic, talented people who share a passion for excellence in building the next generation of networking technologies—and having fun along the way. Infoblox offers a fast-paced, action-oriented environment. We promote a culture that embraces innovation, change, teamwork, and strong partnerships. Join the winning Infoblox team—our future looks bright, and so will yours. To check out what it’s like to be a Bloxer click here.
Apply Now (Use these links for greater visibility to our recruiters)
submitted by 0xTT to CyberSecurityJobs [link] [comments]


Small misunderstanding in CSF, part 2 Partnership – The CSF DC College Support Program Advantage Children's Scholarship Fund Overview CSF Comments In a Cell Part 4: Building the ULTIMATE M4 GTS  CSF Heat Exchanger, Mosselman Thermostat, Dodson DCT Pan CSF Radiators - YouTube #CISOlife - NIST CSF - Identify - Governance 1 (ID.GV-1)  cybersecurity  cyber  security Quipu Community - Entrevista a Antonio Aladueña gerente de CSF Consulting y Presidente de iustime

Meet the CSF Partners - Center For Strategic Facilitation

  1. Small misunderstanding in CSF, part 2
  2. Partnership – The CSF DC College Support Program Advantage
  3. Children's Scholarship Fund Overview
  4. CSF Comments In a Cell
  5. Part 4: Building the ULTIMATE M4 GTS CSF Heat Exchanger, Mosselman Thermostat, Dodson DCT Pan
  6. CSF Radiators - YouTube
  7. #CISOlife - NIST CSF - Identify - Governance 1 (ID.GV-1) cybersecurity cyber security
  8. Quipu Community - Entrevista a Antonio Aladueña gerente de CSF Consulting y Presidente de iustime
  9. CSF Comments: 10/11/17

CSF scholarships would not be possible without the generosity of CSF's donors, the efforts of CSF partner programs nationwide, and the sacrifices of the families themselves, who pay - on average ... READ CAREFULLY!!! 1st. comment = CSF World Title 7th. comment = CSF Video Title 1st. two to comment their partner's name IN ALL CAPS & HELL IN A CELL = CSF Tag Titles Whoever has the most Ace ... CSF presents the behind the scenes of SEMA 2016. An introspecitve view from some of our partners into what really goes into the show, and what it's all about. In today's video, we'll be replacing the thermostat with one from Mosselman, then, we're adding a CSF front mount heat exchanger, CSF DCT Cooler and the Dodson DCT Pan! ... Exclusive Partner Deals ... Quipu Partner's Community - Conoce a nuestros Partners. Entrevista de Roger Dobaño, Responsable de Asesorías en Quipu a: - Antonio Aladueña gerente de CSF Consulting y Presidente de la Red ... OSOFO KYIRIABOSOM WELCOME TO CSF ️ ️🇬🇭 - Duration: 2:02:01. COMMON SENSE FAMILY 29,954 views. ... Is It OK To Read Your Partner's Phone? - Duration: 7:49. NIST Cybersecurity Framework NIST CSF - Identify - Governance 1 (ID.GV-1) Organizational information security policy is established Does the organization hav... 1st. Comment=CSF World Title 7th. Comment=CSF Video Title 1st. two to Comment their partner's name IN ALL CAPS=CSF Tag Titles Whoever has the most Ace Points=CSF Ace Title. Thanks to CSF-DC and our partners, our scholars are transitioning successfully from high school to college to career. Together, we mentor students with promise and show them the path to success.